Research Specialist - Cell Culture

We are seeking a Research Associate to join the Chemical Biology team at Merck in Cambridge, MA. This position will be responsible for supporting various aspects of drug discovery, particularly focusing on cell line maintenance, differentiation, and characterization. Additionally, the successful candidate will play a crucial role in designing and executing cell-based assays and biochemical assays.

Key Responsibilities:

• Support multiple ongoing large-scale cell-based projects that are critical to the success and future of the department.
• Lab work will include cell culturing, cell proliferation, protein isolation, and viral transduction.
• Operate and maintain laboratory instrumentation and robotics, including liquid sample handling platforms.
• Preparation of cell pellets for histological processing.
• Provide vials of tested, frozen cell lines to scientists.
• Isolate and cryopreserve primary PBMCs and further cell subsets from both whole blood and leukopaks.
• Isolate a variety of cell types from fresh blood daily in a timely manner.
• Isolate serum from whole blood.
• Maintain sterile technique while culturing isolated primary cells.
• Perform established flow cytometry QC protocols on a routine basis and analyze results.
• Generate and analyze data with the highest Data Integrity standards to include identifying and reporting unusual results/outcomes.
• Operate and maintain laboratory instrumentation including Mycoplasma onsite testing & clean-up as warranted.
• Interact with senior staff members as necessary.
• Ensure compliance with all R&D data integrity practices, ethics codes, standards and training, and safety training and practice
• Maintain training and compliance in areas of health and safety, security, environmental and operational aspects of daily activities in the working environment.
  
  

Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities of this job at any time