Senior Scientist, Immunology

About Synolo Therapeutics:

Synolo Therapeutics, an early-stage biotechnology company launched by RA Capital, is pioneering the development of precision-targeted immunotherapies. Powered by computational protein design and proprietary technologies which yield biological data sets at unprecedented scale and resolution, we are building a pipeline of first-in-class multi-specific biologics with novel functionalities. Synolo was founded by pioneers in the field of protein design and engineering, synthetic biology, DNA sequencing, immunology, and biologics drug discovery and development.

About RA Capital:

RA Capital Management funds and builds healthcare and life science companies using an evidence-based investment approach informed by TechAtlas, a think tank within RA Capital which analyzes scientific and clinical data from academic literature and industry sources to anticipate how breakthroughs might impact industry stakeholders, physicians, patients, and policymakers. TechAtlas' analyses are captured in a unique collection of competitive landscapes, or ‘maps’, that identify competitive therapeutics, diagnostics, research tools, and/or technological capabilities in a given area.

About the Role:

Synolo Therapeutics is seeking an innovative and collaborative Senior Scientist in Immunology to join our fast-paced startup and work alongside a highly dynamic team to advance multi-specific biologics. As a key scientific contributor, you will develop and execute immune assays to evaluate drug leads, working cross-functionally to drive our drug discovery and development efforts. In our highly supportive, team-driven environment, your creativity and expertise will help shape our science and accelerate our mission to bring transformative medicines to patients in need.

Key Responsibilities:

• Contribute to and support research activities and project goals for the immunology group
• Develop, optimize, and run immune assays using primary cells and cell lines to characterize muti-specific biologics leads (ex: ELISA, MSD, flow cytometry, luminescence reporter assays, co-culture assay, cytotoxicity assay)
• Generate, engineer, and maintain cultures and stocks of immortalized cell lines and primary human cell samples (ex: PBMCs)
• Analyze, summarize, and communicate experimental results verbally and in writing
• Record data and maintain an electronic lab notebook (ELN)
• Work collaboratively in a start up environment
  
  
  

Qualifications & Skills:

• Proven expertise with immunological techniques, including ELISA, MSD and flow cytometry
• Extensive experience with current molecular biology and cell biology techniques, including mammalian cell culture, reporter assays, transfection, and transduction
• Experience in designing in vivo studies for demonstrating pre-clinical activity of novel therapeutics
• Deep understanding of biologics and antibodies, with hands-on experience in their development and application
• Strong analytical mindset, with exceptional attention to detail and the ability to prioritize and manage multiple projects in a fast-paced environment
• Team-driven and adaptable, with the ability to build strong cross-functional relationships and contribute to a collaborative research environment
• Clear and effective communicator, both written and verbal
  
  
  

Education & Experiences:

• We welcome applications from individuals with diverse experiences who are excited to work in a fast-moving biotech environment. The qualifications for Senior Scientist are:
• PhD in Immuno-Oncology, Immunology, Cell Biology, or a related field with 3+ years of industry experience, Or
• MS with 5+ years of industry experience, Or
• BS with 8+ years industry experience
  
  
  

Preferred Experience:

• Hands-on experience with characterizing biologics through cell-based immune assays
• Hands-on experience with running multi-color flow cytometry
• Industry experience
  
  
  

At Synolo Therapeutics, we are committed to fostering a diverse and inclusive work environment where all individuals are valued and treated with dignity. We believe that diversity drives innovation and strengthens our ability to make a meaningful impact through our work. We are committed to being an equal opportunity employer who ensures that all qualified applicants receive equal consideration for employment without regard to neurodiversity, race/ethnicity, color, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.