Associate Scientist/Scientist, Biology

JLSa2 is a recently launched seed-stage venture backed company located in South San Francisco focused on developing novel multifunctional protein-drug conjugate therapies to address human metabolic diseases and other non-oncology related diseases.

The company is seeking Associate Scientist/Scientist to contribute to the discovery biology group through hands-on in vitro characterization of multifunctional biologic conjugates with cell-based bioassays and support coordination of in vitro and in vivo characterization of the multifunctional conjugates as well as contribute to multiple aspects of product development as molecules progress from research stage into early clinical development.

Responsibilities

The candidate will perform functional screening assays and mechanism of action studies of research candidates using ELISA, cell-based bioassays, and kinetic-based binding assay formats (eg: Octet or Gator). The candidate will work collaboratively with the conjugation and analytical teams, as well as senior leadership, to ensure data integration across functional areas to facilitate rapid decision making and efficient product iteration cycle time. This position is expected to be on site at our SSF facility.

Qualifications

• PhD in molecular biology, cell biology, biochemistry, or related scientific field with 3-5 years of industry experience or BS/MS in and minimum 10-12 years of industry experience in potency assays and mammalian cell culture is required.
• Experience with cell-based potency and bioassay methods, reporter assays, proliferation assays, and other related assays, attention to detail and ability to organize multiple experiments with multiple analytes is required.
• Flexibility to work on multiple projects in a fast-paced start up environment is essential.
• Experience with cell-based and biochemical assay development and screening is essential.
• Good communication skills are essential.
• Demonstrated proficiency in designing experiments, interpreting, and presenting data is preferred.
• Prior experience with bioconjugates and assay automation is desirable.
• Management experience is a plus.
• Experience using Microsoft Office, and data analysis software like PRISM, PLA, or Softmax Pro is a plus.
  
  
  

Salary Range: $115,000 to $125,000 (Compensation and level will be commensurate with experience and expertise and could fall outside of the stated range)

The offered JLSa2 benefits package includes industry competitive salary, medical, dental, and vision insurances, life insurance, 401K plan, non-accruing PTO, and early-stage equity.